Methylophiopogonanone a attenuates pulmonary fibrosis by inhibiting <scp>SPP1</scp> ‐mediated macrophage polarization via the <scp>PI3K</scp> /Akt pathway
This study identifies that MOA is a promising natural compound that alleviates pulmonary fibrosis by inhibiting SPP1-mediated macrophage polarization via the PI3K/Akt pathway.
Authors
- He Xu (ORCID: https://orcid.org/0000-0001-6559-2957)
- Yunyu Shi (ORCID: https://orcid.org/0000-0002-1348-4759)
- Xudong Song
- Na Mao (ORCID: https://orcid.org/0000-0001-8947-3258)
- F YANG
- Xia Li (ORCID: https://orcid.org/0000-0002-6068-5182)
- Liangdan Sun
- Yanlei Ge
- Fuyu Jin
- Dingjie Xu
- Weiran Jia
Institutions
- North China University of Science and Technology (CN)
- Shanxi Medical University (CN)
- First Hospital of Shanxi Medical University (CN)
Publication Details
- Journal
- Animal Models and Experimental Medicine
- Published
- 2026-03-09
- DOI
- https://doi.org/10.1002/ame2.70157
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00