Systematic evaluation of medication adherence determinants across 137 active substances on population-level real-world health data
Thus, IMAS represents a person-level metric that captures baseline medication-taking behaviour across therapeutic classes and predicts both medication adherence as well as health outcomes. Our analysis suggests that medication-taking behaviour represents a broader patient-level phenomenon manifesting consistently across medications, suggesting its potential for personalised interventions in clinical practice and more efficient public health strategies and policies.
Authors
- Taavi Tillmann (ORCID: https://orcid.org/0000-0002-8428-3719)
- Kerli Mooses (ORCID: https://orcid.org/0000-0002-3651-6063)
- Maria Malk
- Sulev Reisberg (ORCID: https://orcid.org/0000-0001-6835-9632)
- Sirli Tamm (ORCID: https://orcid.org/0009-0009-8565-3572)
- Maarja Pajusalu (ORCID: https://orcid.org/0000-0001-9715-0678)
- Helene Loorents
- Nikita Umov (ORCID: https://orcid.org/0009-0002-6231-0998)
- Johannes Holm
- Raivo Kolde
- Marek Oja
- Hanna Keidong
- Jaak Vilo
Institutions
- University of Tartu (EE)
Publication Details
- Journal
- Communications Medicine
- Published
- 2026-03-09
- DOI
- https://doi.org/10.1038/s43856-026-01515-8
- Primary Topic
- Medication Adherence and Compliance
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission
- Eesti Teadusagentuur
- HORIZON EUROPE Framework Programme
- Research Executive Agency
- European Regional Development Fund