Clinical Validation of Plasma p‐217tau in Neurological Diseases

ALS and iNPH are two major pitfalls for the clinical application of plasma p-217tau as a biomarker of AD. Lower motor neuron injury in ALS and cognitive dysfunction in iNPH were both found to be associated with elevated plasma p-217tau levels.

Authors

Institutions

Publication Details

Journal
Annals of Clinical and Translational Neurology
Published
2026-03-09
DOI
https://doi.org/10.1002/acn3.70359
Primary Topic
Amyotrophic Lateral Sclerosis Research
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Kunihiko Ishizawa, Takumi Nakamura, Masakuni Amari, Takashi Sugawara et al.
Annals of Clinical and Translational Neurology
Amyotrophic Lateral Sclerosis Research
article

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Kunihiko Ishizawa, Takumi Nakamura, Masakuni Amari, Takashi Sugawara, Masamitsu Takatama, Seiji Kinoshita, Ryoma Takahashi, Hiroo Kasahara, Mikio Shoji, Yoshio Ikeda, Chikage Uchida, Tetsuya Ueda, Takeshi Kawarabayashi, Kentaro Hashimoto
article en

Abstract

ALS and iNPH are two major pitfalls for the clinical application of plasma p-217tau as a biomarker of AD. Lower motor neuron injury in ALS and cognitive dysfunction in iNPH were both found to be associated with elevated plasma p-217tau levels.

Annals of Clinical and Translational Neurology
Hirosaki University (JP), Maebashi Institute of Technology (JP), Gunma University (JP), Sumco Corporation (Japan) (JP)
Good health and well-being
Openalex Percentile: Top 35%
Amyotrophic Lateral Sclerosis Research
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.