The Viral-Oncogenic Pathway — 11 Mechanistic Analogies and Pharmacological Proof with Aspirin.

Known oncogenic viruses — EBV, HCV, HBV, HPV, HHV-8, HTLV-1, MCV, H. pylori — produce exactly the same inflammation, the same coagulation and the same biofilm as any other pathogenic virus. 11 biological mechanisms are here systematically compared between SARS-CoV-2 (prototype of the common virus in acute form) and oncogenic viruses (silent chronic form): inflammation, coagulation, biofilm, NF-κB, endothelial damage, NETs, hypoxia/HIF-1α, iron addiction, Warburg Effect, local immunosuppression, fibrin as scaffold. Result: 11 out of 11. Identical mechanism. Only time changes. Aspirin simultaneously blocks inflammation, coagulation and biofilm — and reduces the incidence of at least 7 tumour types. Simon et al. (NEJM Evidence 2022) demonstrates a 31–38% reduction of hepatocellular carcinoma in patients with chronic viral hepatitis. This is the inverse pharmacological proof: block the viral pathway → the tumour decreases. The difference between a common virus and an oncogenic virus is not in the mechanism. It is in the time and visibility.