Agentic AI for Ageing Healthcare Systems in Advanced Economies: A Structured Review of Evidence, Institutional Barriers, and a Sociotechnical Implementation Roadmap

Advanced economies face a compounding demographic crisis: populations aged 65 and over will reach 30–40% in several nations by 2050, ageing-related expenditure already absorbs up to 18% of GDP in the most affected economies, and demographic ageing is projected to reduce annual GDP growth by 0.3–1.2 percentage points by 2035. Conventional policy instruments have failed to resolve pressures that include severe long-term care workforce shortfalls across leading ageing economies and per-capita elderly care costs running 3–5 times those of working-age cohorts. This structured narrative review of 81 sources (2020–2025) evaluates whether Agentic AI defined as autonomous, goal-directed systems capable of multi-step workflow coordination can support structural adaptation in ageing health systems. A consistent finding is that implementation outcomes are determined by institutional conditions rather than algorithmic performance, and evidence strength is inversely correlated with intervention complexity. Three contributions are presented: the Agentic AI Framework (AAF 3.0); a cross-domain synthesis formalising the inverse evidence–complexity relationship; and a phased sociotechnical roadmap integrating governance sequencing, reimbursement reform, and equity safeguards. Short-term productivity gains are documented; macroeconomic fiscal moderation remains empirically unvalidated.

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Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-03-09
DOI
https://doi.org/10.5281/zenodo.18919707
Primary Topic
Global Health Care Issues
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article
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article

Agentic AI for Ageing Healthcare Systems in Advanced Economies: A Structured Review of Evidence, Institutional Barriers, and a Sociotechnical Implementation Roadmap

Rachel Wei Gee Ooi, Periasamy Baskar
Zenodo (CERN European Organization for Nuclear Research)
Global Health Care Issues
article

Agentic AI for Ageing Healthcare Systems in Advanced Economies: A Structured Review of Evidence, Institutional Barriers, and a Sociotechnical Implementation Roadmap

Rachel Wei Gee Ooi, Periasamy Baskar
article en

Abstract

Advanced economies face a compounding demographic crisis: populations aged 65 and over will reach 30–40% in several nations by 2050, ageing-related expenditure already absorbs up to 18% of GDP in the most affected economies, and demographic ageing is projected to reduce annual GDP growth by 0.3–1.2 percentage points by 2035. Conventional policy instruments have failed to resolve pressures that include severe long-term care workforce shortfalls across leading ageing economies and per-capita elderly care costs running 3–5 times those of working-age cohorts. This structured narrative review of 81 sources (2020–2025) evaluates whether Agentic AI defined as autonomous, goal-directed systems capable of multi-step workflow coordination can support structural adaptation in ageing health systems. A consistent finding is that implementation outcomes are determined by institutional conditions rather than algorithmic performance, and evidence strength is inversely correlated with intervention complexity. Three contributions are presented: the Agentic AI Framework (AAF 3.0); a cross-domain synthesis formalising the inverse evidence–complexity relationship; and a phased sociotechnical roadmap integrating governance sequencing, reimbursement reform, and equity safeguards. Short-term productivity gains are documented; macroeconomic fiscal moderation remains empirically unvalidated.

Zenodo (CERN European Organization for Nuclear Research)
Human Sciences Research Council (ZA), Physicians Committee for Responsible Medicine (US), Nanyang Technological University (SG), Antioch University (US), College Of Certified Psychophysiologists (US)
Decent work and economic growth
Openalex Percentile: Top 33%
Global Health Care Issues
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Agentic AI for Ageing Healthcare Systems in Advanced Economies: A Structured Review of Evidence, Institutional Barriers, and a Sociotechnical Implementation Roadmap — Rachel Wei Gee Ooi, Periasamy Baskar · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS