Real-world precision medicine data in metastatic prostate cancer — a retrospective cohort study
<i>PTEN</i>, and <i>HRR</i> mutations were associated with shorter OS in both mHSPC and mCRPC. <i>p53</i> mutations are associated with shorter OS only in mHSPC. <i>p53</i> and <i>PTEN</i> mutations were associated with shorter PFS only in mCRPC.
Authors
- Zohair Siddiqui (ORCID: https://orcid.org/0000-0002-2309-6805)
- Jonathan Kapilian (ORCID: https://orcid.org/0000-0003-3684-2173)
- Jacob Stone
- Derek Tran (ORCID: https://orcid.org/0000-0002-3274-363X)
- Awais Paracha
- Adrian Choppa
- Anthony J Corsi
- Margot Noyelle
- Xin-Hua Zhu
Institutions
- Northwell Health (US)
- Thomas Jefferson University (US)
- University of Tennessee Health Science Center (US)
- California Pacific Medical Center (US)
- Donald & Barbara Zucker School of Medicine at Hofstra/Northwell (US)
- Northwell Health Orthopaedic Institute (US)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-03-09
- DOI
- https://doi.org/10.3389/fonc.2026.1772860
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00