Epstein-Barr Virus Antibodies to Differentiate Multiple Sclerosis From Other Neuroinflammatory Diseases
Results of this case-control study reveal that persistent high-level EBNA-1 peptide antibody titers may serve as a reliable biomarker for differentiating MS from MOGAD, and NMOSD.
Authors
- Markus Breu (ORCID: https://orcid.org/0000-0003-3825-5749)
- Lauren Krupp (ORCID: https://orcid.org/0000-0001-7003-807X)
- Lisa Weidner (ORCID: https://orcid.org/0000-0001-9666-6517)
- Barbara Kornek (ORCID: https://orcid.org/0000-0002-1851-6967)
- Gabriel Bsteh (ORCID: https://orcid.org/0000-0002-0825-0851)
- Hannes Vietzen (ORCID: https://orcid.org/0000-0003-3993-6538)
- S. Berger (ORCID: https://orcid.org/0000-0003-4633-8245)
- Markus Ponleitner (ORCID: https://orcid.org/0000-0002-3709-1845)
- Kevin M. Rostasy (ORCID: https://orcid.org/0000-0002-2180-5321)
- Jeremy Vann Camp (ORCID: https://orcid.org/0000-0002-9040-5786)
- Lee Benson (ORCID: https://orcid.org/0000-0002-1407-1825)
- Gregory Scott Aaen (ORCID: https://orcid.org/0000-0002-0408-2053)
- Georgia Koukou (ORCID: https://orcid.org/0009-0003-1588-6633)
- Romana Höftberger (ORCID: https://orcid.org/0000-0002-5769-1100)
- Marianne Graninger (ORCID: https://orcid.org/0000-0002-2152-7798)
- Laura M. Kühner (ORCID: https://orcid.org/0009-0000-5830-9009)
- Hans P. Lassmann
- Elisabeth Puchhammer-Stöckl
- Charlotte Pistorius
- Henrieke Saucke
- Franziska Kauth (ORCID: https://orcid.org/0009-0005-8307-5829)
- Simon Sommer (ORCID: https://orcid.org/0000-0002-9354-6285)
- Christof Jungbauer
- Timothy E. Lotze
- Eva-Maria Wendel
- Soe Mar
- Paulus Rommer
- Raphael Reinecke
- Bianca Weinstock-Guttman
- Emmanuelle L. Waubant
- Markus Reindl
- Tanuja Chitnis
- T. Charles Casper
- Thomas Berger
Institutions
- Boston Children's Hospital (US)
- Harvard University (US)
- Innsbruck Medical University (AT)
- Witten/Herdecke University (DE)
- University of California, San Francisco (US)
- Universität Innsbruck (AT)
- Washington University in St. Louis (US)
- University of Utah (US)
- Loma Linda University (US)
- Paracelsus Medical University (AT)
- Massachusetts General Hospital (US)
- Olgahospital (DE)
- Texas Children's Hospital (US)
- Jacobs Institute (US)
- Boston Children's Museum (US)
- Klinikum Stuttgart (DE)
- Austrian Red Cross (AT)
- New York University (US)
- Medical University of Vienna (AT)
Publication Details
- Journal
- JAMA Neurology
- Published
- 2026-03-09
- DOI
- https://doi.org/10.1001/jamaneurol.2026.0240
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00