Post‐Radiation Granuloma Annulare: A Series of Three Cases

ABSTRACT We report typical cases of biopsy confirmed granuloma annulare occurring on irradiated skin in the context of breast cancer in three women in their seventies. The lesions appeared immediately after start of irradiation in one patient, 4 and 15 months after the end of radiation treatment in the other two. The lesions eventually spread elsewhere on the body in two patients. Similar to morphea, which is a well‐known side effect of irradiation, we believe that radiotherapy can induce tissue damage, leading to dermal inflammation ultimately responsible for the emergence of granuloma annulare.

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Publication Details

Journal
JEADV Clinical Practice
Published
2026-03-09
DOI
https://doi.org/10.1002/jvc2.70314
Primary Topic
Skin Diseases and Diabetes
Type
article
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article

Post‐Radiation Granuloma Annulare: A Series of Three Cases

M. Mitcov, D. Lipsker, Léa Scheid
JEADV Clinical Practice
Skin Diseases and Diabetes
article

Post‐Radiation Granuloma Annulare: A Series of Three Cases

M. Mitcov, D. Lipsker, Léa Scheid
article en

Abstract

ABSTRACT We report typical cases of biopsy confirmed granuloma annulare occurring on irradiated skin in the context of breast cancer in three women in their seventies. The lesions appeared immediately after start of irradiation in one patient, 4 and 15 months after the end of radiation treatment in the other two. The lesions eventually spread elsewhere on the body in two patients. Similar to morphea, which is a well‐known side effect of irradiation, we believe that radiotherapy can induce tissue damage, leading to dermal inflammation ultimately responsible for the emergence of granuloma annulare.

JEADV Clinical Practice
Hôpitaux Universitaires de Strasbourg (FR), Université de Strasbourg (FR)
Good health and well-being
Openalex Percentile: Top 28%
Skin Diseases and Diabetes
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