miR-500a-3p negatively regulates SOCS2 and participates in the proliferation, glycolysis, and apoptosis of HCC cells via the JAK2/STAT5 pathway

This study reveals that miR-500a-3p promotes proliferation and glycolysis while inhibiting apoptosis of HCC cells by negatively regulating SOCS2 and activating the JAK2/STAT5 pathway.

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Publication Details

Journal
Journal of Applied Biomedicine
Published
2026-03-09
DOI
https://doi.org/10.32725/jab.2026.002
Primary Topic
Cytokine Signaling Pathways and Interactions
Type
article
Field-Weighted Citation Impact
0.00
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article

miR-500a-3p negatively regulates SOCS2 and participates in the proliferation, glycolysis, and apoptosis of HCC cells via the JAK2/STAT5 pathway

Shan Li, Wei Liu, Wei Luo
Journal of Applied Biomedicine
Cytokine Signaling Pathways and Interactions
article

miR-500a-3p negatively regulates SOCS2 and participates in the proliferation, glycolysis, and apoptosis of HCC cells via the JAK2/STAT5 pathway

Shan Li, Wei Liu, Wei Luo
article en

Abstract

This study reveals that miR-500a-3p promotes proliferation and glycolysis while inhibiting apoptosis of HCC cells by negatively regulating SOCS2 and activating the JAK2/STAT5 pathway.

Journal of Applied BiomedicineVol. 24(1)
China Three Gorges University (CN), The Central Hospital of Xiao gan (CN)
Good health and well-being
Openalex Percentile: Top 28%
Cytokine Signaling Pathways and Interactions
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miR-500a-3p negatively regulates SOCS2 and participates in the proliferation, glycolysis, and apoptosis of HCC cells via the JAK2/STAT5 pathway — Shan Li, Wei Liu, et al. · Journal of Applied Biomedicine (2026) | TGRS Research Map | TGRS