Quantitative susceptibility mapping in pediatric neuroimaging: a systematic review of applications and advancements
QSM emerges as a valuable tool in pediatric neuroimaging, offering quantitative biomarkers for brain development, disease monitoring, and potential clinical translation. Despite promising results, challenges remain, including motion artifacts, lack of normative pediatric data, and methodological heterogeneity. Future research should focus on longitudinal designs, standardization of protocols, and integration with complementary imaging modalities. With further refinement, QSM has the potential to become an integral component of pediatric neuroradiological assessment.
Authors
- F. Tortora
- Lorenzo Ugga (ORCID: https://orcid.org/0000-0001-7811-4612)
- Mario Tortora (ORCID: https://orcid.org/0000-0002-4745-3061)
- S Capasso
- Ferdinando Caranci (ORCID: https://orcid.org/0000-0003-4381-8323)
- Filippo Arrigoni (ORCID: https://orcid.org/0000-0002-5508-1149)
- Francesco Pacchiano
- Mario Cirillo
- Kshitij Mankad
Institutions
- University of Campania "Luigi Vanvitelli" (IT)
- Great Ormond Street Hospital (GB)
- Federico II University Hospital (IT)
- Ospedale dei Bambini Vittore Buzzi (IT)
- University College London (GB)
- University of Naples Federico II (IT)
Publication Details
- Journal
- Pediatric Radiology
- Published
- 2026-03-09
- DOI
- https://doi.org/10.1007/s00247-026-06565-7
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Università degli Studi di Napoli Federico II