Validation of a flow cytometric competitive efflux assay for assessing clinically important drugs as canine P-glycoprotein substrates
These results imply that P-gp-deficient dogs may be at increased risk of adverse effects if treated with apomorphine, capromorelin, enrofloxacin, or moxidectin, depending on the dose administered.
Authors
- Katrina L. Mealey (ORCID: https://orcid.org/0000-0003-1614-2903)
- Neal S. Burke
Institutions
- Washington State University (US)
Publication Details
- Journal
- American Journal of Veterinary Research
- Published
- 2026-03-09
- DOI
- https://doi.org/10.2460/ajvr.25.11.0419
- Primary Topic
- Drug Transport and Resistance Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00