Sex-Specific Cardiometabolic Profiles and Severity of Liver Fibrosis

In this study, the presence of 2 or more CMRFs was associated with a greater increase in risk of significant fibrosis for women compared with men. Central adiposity and glucose intolerance were also associated with greater increases in risk among women.. These findings support the need for sex-specific screening approaches.

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Publication Details

Journal
JAMA Network Open
Published
2026-03-09
DOI
https://doi.org/10.1001/jamanetworkopen.2026.0863
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Sex-Specific Cardiometabolic Profiles and Severity of Liver Fibrosis

Somaya Albhaisi, Steve Kim, Norah Terrault, Jennifer L. Dodge
JAMA Network Open
Liver Disease Diagnosis and Treatment
article

Sex-Specific Cardiometabolic Profiles and Severity of Liver Fibrosis

Somaya Albhaisi, Steve Kim, Norah Terrault, Jennifer L. Dodge
article en

Abstract

In this study, the presence of 2 or more CMRFs was associated with a greater increase in risk of significant fibrosis for women compared with men. Central adiposity and glucose intolerance were also associated with greater increases in risk among women.. These findings support the need for sex-specific screening approaches.

JAMA Network OpenVol. 9(3)
University of Southern California (US)
F. Hoffmann-La Roche, National Institutes of Health, Genentech, National Institute of Diabetes and Digestive and Kidney Diseases
Gender equality
Openalex Percentile: Top 30%
Liver Disease Diagnosis and Treatment
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