Successful prosthetic graft replacement for middle aortic syndrome in a 9-year-old child

Middle aortic syndrome is a rare vascular disorder characterised by segmental narrowing of the distal thoracic aorta and/or proximal abdominal aorta, often accompanied by renal artery involvement. The condition may arise from genetic abnormalities, acquired factors, or idiopathic causes. In this study, we report the case of a 9-year-old boy who was found to have hypertension during a routine school health examination. Computed tomography angiography confirmed the diagnosis of middle aortic syndrome, revealing long-segment stenosis of the distal thoracic aorta. Following a comprehensive assessment, the patient underwent descending aortic reconstruction with a 14 mm Intergard knitted vascular graft. At the 6-month follow-up, imaging demonstrated satisfactory graft patency, and the patient's blood pressure remained well-controlled without the need for antihypertensive medications.

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Publication Details

Journal
Cardiology in the Young
Published
2026-03-09
DOI
https://doi.org/10.1017/s1047951126111330
Primary Topic
Renal and Vascular Pathologies
Type
article
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article

Successful prosthetic graft replacement for middle aortic syndrome in a 9-year-old child

Hong Zhao, Yiqing Pu
Cardiology in the Young
Renal and Vascular Pathologies
article

Successful prosthetic graft replacement for middle aortic syndrome in a 9-year-old child

Hong Zhao, Yiqing Pu
article en

Abstract

Middle aortic syndrome is a rare vascular disorder characterised by segmental narrowing of the distal thoracic aorta and/or proximal abdominal aorta, often accompanied by renal artery involvement. The condition may arise from genetic abnormalities, acquired factors, or idiopathic causes. In this study, we report the case of a 9-year-old boy who was found to have hypertension during a routine school health examination. Computed tomography angiography confirmed the diagnosis of middle aortic syndrome, revealing long-segment stenosis of the distal thoracic aorta. Following a comprehensive assessment, the patient underwent descending aortic reconstruction with a 14 mm Intergard knitted vascular graft. At the 6-month follow-up, imaging demonstrated satisfactory graft patency, and the patient's blood pressure remained well-controlled without the need for antihypertensive medications.

Cardiology in the Young
National Clinical Research (US), Zhejiang University (CN)
Good health and well-being
Openalex Percentile: Top 28%
Renal and Vascular Pathologies
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Successful prosthetic graft replacement for middle aortic syndrome in a 9-year-old child — Hong Zhao, Yiqing Pu · Cardiology in the Young (2026) | TGRS Research Map | TGRS