DBT more efficacious than SSRI in reducing suicidality in borderline personality disorder

Six months of dialectical behavior therapy (DBT) was more efficacious than a 6‐month course of treatment with a selective serotonin reuptake inhibitor (SSRI) antidepressant in reducing suicide‐related events in patients with borderline personality disorder, a randomized trial has found. However, SSRI treatment was more efficacious than DBT in reducing diagnoses of major depressive disorder at 6 months.

Publication Details

Journal
The Brown University Psychopharmacology Update
Published
2026-02-23
DOI
https://doi.org/10.1002/pu.31417
Primary Topic
Personality Disorders and Psychopathology
Type
article
Field-Weighted Citation Impact
0.00
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article

DBT more efficacious than SSRI in reducing suicidality in borderline personality disorder

The Brown University Psychopharmacology Update
Personality Disorders and Psychopathology
article

DBT more efficacious than SSRI in reducing suicidality in borderline personality disorder

article en

Abstract

Six months of dialectical behavior therapy (DBT) was more efficacious than a 6‐month course of treatment with a selective serotonin reuptake inhibitor (SSRI) antidepressant in reducing suicide‐related events in patients with borderline personality disorder, a randomized trial has found. However, SSRI treatment was more efficacious than DBT in reducing diagnoses of major depressive disorder at 6 months.

The Brown University Psychopharmacology UpdateVol. 37(3)
Good health and well-being
Openalex Percentile: Top 34%
Personality Disorders and Psychopathology
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DBT more efficacious than SSRI in reducing suicidality in borderline personality disorder · The Brown University Psychopharmacology Update (2026) | TGRS Research Map | TGRS