Comparative efficacy of different doses of mesenchymal stem cells derived from different tissue sources for knee osteoarthritis: a systematic review and network meta-analysis of randomized controlled trials
This NMA identifies M_ADSCS as the most effective MSC treatment for KOA, with balanced efficacy and safety profiles. These findings provide valuable insights for optimizing MSC therapy and highlight the need for further research on dosing and tissue sources.
Authors
- Yu Pan (ORCID: https://orcid.org/0000-0002-5703-5322)
- Xueyi Ni
- Hainan Jin
- Ruimou Xie
- Jingyang Yu
- Yanlin Zhang
- Yutong Feng
Institutions
- Beijing Tsinghua Chang Gung Hospital (CN)
- University College London (GB)
Publication Details
- Journal
- PeerJ
- Published
- 2026-03-09
- DOI
- https://doi.org/10.7717/peerj.20776
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00