Prognostic impact of myelodysplasia-related gene mutations in ELN-2022 favorable-risk acute myeloid leukemia subtypes
The presence of a single MRG mutation did not confer a worse prognosis in favorable-risk AML, whereas a high MRG mutation burden (≥2 mutations) was independently associated with poorer LFS. This study suggests that quantifying the MRG mutation burden may inform risk stratification in this patient population.
Authors
- Shilong Ying (ORCID: https://orcid.org/0000-0001-9191-143X)
- Wei Zheng (ORCID: https://orcid.org/0000-0003-1206-9243)
- Furun An
- Qian Li (ORCID: https://orcid.org/0000-0003-1300-3377)
- Jian Sun (ORCID: https://orcid.org/0000-0003-0067-5967)
- Yuanyuan Zhu
- Z M Zhai
- Jingwen Li
- Fang Fang
- Lulu Zhang
Institutions
- Anhui Medical University (CN)
- Wenzhou Medical University (CN)
- The People's Hospital Tongling (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
- Zhejiang Taizhou Hospital (CN)
- First Affiliated Hospital Zhejiang University (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2026-03-09
- DOI
- https://doi.org/10.1080/07853890.2026.2636337
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00