Biological Performance of Modified Glass Ionomer Cement: Antibacterial Activity, Cytocompatibility, and Rabbit Pulpal Response
Incorporation of 10% CHX markedly enhanced the antibacterial properties of BIOGIC but increased cytotoxicity. BIOGIC formulations containing TCP and low-dose TCTP improved pulp cell viability and maintained favourable pulpal responses. These modified BIOGIC materials show promise as bioactive, pulp-compatible alternatives to conventional GIC, although CHX-containing formulations should be used with caution owing to their cytotoxic effects.
Authors
- Sareepah Manmoo (ORCID: https://orcid.org/0000-0002-8654-5428)
- Peerapon Sornying (ORCID: https://orcid.org/0000-0003-1169-9446)
- Nattapon Rotpenpian (ORCID: https://orcid.org/0000-0002-0130-9179)
- Krittee Dejyong (ORCID: https://orcid.org/0000-0002-4631-3745)
- Saowakon Indoung
Institutions
- Prince of Songkla University (TH)
Publication Details
- Journal
- International Dental Journal
- Published
- 2026-03-09
- DOI
- https://doi.org/10.1016/j.identj.2026.109491
- Primary Topic
- Dental materials and restorations
- Type
- article
- Field-Weighted Citation Impact
- 0.00