The gut microbiota remodes amino acid and lipid metabolism in incomplete revascularization of CHD with phlegm-dampness syndrome: an integrated multiomics and network pharmacology study
IR-CHD patients with PD TCM Syndrome have amino acid and lipid metabolic disorders and that the gut microbiota plays an important role in their metabolic regulation. This study also provides an evidence-based strategy for exploring the biological basis of TCM Syndrome differentiation, which is helpful for the translation of TCM theory into precision medicine practice.
Authors
- Haiming Cao (ORCID: https://orcid.org/0009-0004-7548-289X)
- Taohua Lan
- Wenhua Shi (ORCID: https://orcid.org/0000-0003-4988-2641)
- W. L. Xu (ORCID: https://orcid.org/0000-0002-9205-1694)
- Haining Zhao
- Weihui Lu
- Xiaoqing Li
- Tong Liu
- Wei Jiang
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Ji Hua Laboratory (CN)
- Guangdong Provincial Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2026-03-09
- DOI
- https://doi.org/10.3389/fmolb.2026.1748007
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Traditional Chinese Medicine Bureau of Guangdong Province