mSphere of Influence: The power of <i>in situ</i> —structural biology without leaving “home”

Nicholas A. Wood works in the field of biophysics with an emphasis on <i>in situ</i> protein structures in microbiological systems. In this mSphere of Influence article, he reflects on the power and limitations of AlphaFold, open questions in structural biology, and the cross-disciplinary potential of microbiological training.

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Publication Details

Journal
mSphere
Published
2026-03-09
DOI
https://doi.org/10.1128/msphere.00798-25
Primary Topic
Bacterial Genetics and Biotechnology
Type
article
Field-Weighted Citation Impact
0.00
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article

mSphere of Influence: The power of in situ —structural biology without leaving “home”

Nicholas Wood
mSphere
Bacterial Genetics and Biotechnology
article

mSphere of Influence: The power of in situ —structural biology without leaving “home”

Nicholas Wood
article en

Abstract

Nicholas A. Wood works in the field of biophysics with an emphasis on <i>in situ</i> protein structures in microbiological systems. In this mSphere of Influence article, he reflects on the power and limitations of AlphaFold, open questions in structural biology, and the cross-disciplinary potential of microbiological training.

mSphere
Medical College of Wisconsin (US)
Openalex Percentile: Top 29%
Bacterial Genetics and Biotechnology
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mSphere of Influence: The power of <i>in situ</i> —structural biology without leaving “home” — Nicholas Wood · mSphere (2026) | TGRS Research Map | TGRS