Tisdale-score-based risk stratification of QTc prolongations in hospitalized patients receiving azole antifungal therapy—a retrospective study
Patients prescribed systemic azole antifungals are at risk of QTc prolongation due to regular use of multiple QT-drugs. However, relevant QTc prolongations were rare in the patient population studied. The Tisdale-score achieved a good sensitivity for the identification of patients at risk for QTc prolongation.
Authors
- Dorothea Strobach (ORCID: https://orcid.org/0000-0003-2871-0605)
- Michael Irlbeck (ORCID: https://orcid.org/0000-0002-7868-265X)
- Ute Amann (ORCID: https://orcid.org/0000-0001-5913-6031)
- Julian Steinbrech (ORCID: https://orcid.org/0009-0008-2598-1497)
- Sebastian Clauß
Institutions
- University of Colorado Hospital (US)
- LMU Klinikum (DE)
- German Centre for Cardiovascular Research (DE)
- ERN GUARD-Heart (NL)
- Centre of Experimental Medicine of the Slovak Academy of Sciences (SK)
- Center for Clinical Research (United States) (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2026-03-09
- DOI
- https://doi.org/10.3389/fcvm.2026.1685152
- Primary Topic
- Cardiac electrophysiology and arrhythmias
- Type
- article
- Field-Weighted Citation Impact
- 0.00