Tenofovir Alafenamide vs. Tenofovir Disoproxil Fumarate in Lowering the Risk of HCC Development in Patients With CHB

Compared with TDF, TAF use was associated with an approximately 71% reduction in HCC hazard. Larger cohorts with longer follow-up are warranted to corroborate these observations.

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Publication Details

Journal
Journal of Gastroenterology and Hepatology
Published
2026-03-08
DOI
https://doi.org/10.1111/jgh.70326
Primary Topic
Hepatitis C virus research
Type
article
Field-Weighted Citation Impact
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article

Tenofovir Alafenamide vs. Tenofovir Disoproxil Fumarate in Lowering the Risk of HCC Development in Patients With CHB

Seung Kak Shin, Soon Koo Baik, Sun Young Yim, Seul Ki Han et al.
Journal of Gastroenterology and Hepatology
Hepatitis C virus research
article

Tenofovir Alafenamide vs. Tenofovir Disoproxil Fumarate in Lowering the Risk of HCC Development in Patients With CHB

Seung Kak Shin, Soon Koo Baik, Sun Young Yim, Seul Ki Han, Seong Hee Kang, Jong Eun Yeon, Young Kul Jung, Tae Hyung Kim, Moon Young Kim, Young‐Sun Lee, Hyung Joon Yim, Yeon Seok Seo, Oh. Sang Kwon, Ji Hoon Kim
article en

Abstract

Compared with TDF, TAF use was associated with an approximately 71% reduction in HCC hazard. Larger cohorts with longer follow-up are warranted to corroborate these observations.

Journal of Gastroenterology and Hepatology
Gachon University (KR), Yonsei University (KR), Korea University (KR)
Openalex Percentile: Top 32%
Hepatitis C virus research
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Tenofovir Alafenamide vs. Tenofovir Disoproxil Fumarate in Lowering the Risk of HCC Development in Patients With CHB — Seung Kak Shin, Soon Koo Baik, et al. · Journal of Gastroenterology and Hepatology (2026) | TGRS Research Map | TGRS