Role of Spatial Heterogeneity in Muscle-Invasive Bladder Cancer on Overall Survival and Immunotherapy Response
Intra-bladder tumor location determines survival and distinct genetic profiles in MIBC. These location-specific alterations predict ICI response and identify novel synthetic lethal targets, guiding precision oncology.
Authors
- Yudai Ishiyama (ORCID: https://orcid.org/0000-0002-8440-6264)
- Arjun K. Venkatesh (ORCID: https://orcid.org/0000-0002-8248-0567)
- Mark Bandyk (ORCID: https://orcid.org/0000-0002-3940-3275)
- Thomas D. Metzner
- Hunter Sceats
- Reynier D. Rodriguez Rosales
- Mohammed Al-Toubat
- Jean-Pierre Kanumuambidi
- K. C. Balaji
- Shelby Sparks
- Nicole Murray
Institutions
- St. George's University (GD)
- University of Utah (US)
- Huntsman Cancer Institute (US)
- Jacksonville University (US)
Publication Details
- Journal
- Cancers
- Published
- 2026-03-09
- DOI
- https://doi.org/10.3390/cancers18050875
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00