Prolonged intermittent theta burst stimulation enhances hippocampal plasticity via GluN2A-mediated signaling
Together, these findings indicate that prolonged iTBS drives coordinated structural, synaptic, and Ca<sup>2+</sup>-dependent plasticity in the hippocampus through GluN2A- and BDNF-dependent mechanisms. This work provides mechanistic insight into how iTBS may induce sustained circuit-level adaptations relevant for therapeutic applications.
Authors
- Andjela Stekić (ORCID: https://orcid.org/0000-0002-2353-2937)
- Marina Zarić Kontić (ORCID: https://orcid.org/0000-0003-1635-9766)
- Milena Milošević (ORCID: https://orcid.org/0000-0002-6138-6766)
- Katarina Mihajlović (ORCID: https://orcid.org/0000-0002-9385-5002)
- Milorad Dragić (ORCID: https://orcid.org/0000-0003-4855-6131)
- Emilija Glavonic (ORCID: https://orcid.org/0000-0002-2053-7716)
- Danica Popović
- Teodora Martić
- T. Radukic
- Ana Jakovljevic
- Marija Adzic Bukvic
- Ivana Stevanovic
- Milica Zeljkovic Jovanovic
Institutions
- University of Belgrade (RS)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2026-03-09
- DOI
- https://doi.org/10.3389/fnagi.2026.1757554
- Primary Topic
- Transcranial Magnetic Stimulation Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00