Chromosomal damage in breast cancer patients undergoing different radiotherapy schemes

Shorter RT scheme with higher dose per fraction may mitigate cytogenetic damage in circulating lymphocytes, offering potential advantages in long-term safety profiles. In vitro chromosomal radiosensitivity, as assessed by CBMN assay is not a hallmark for second primary BC risk.

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Publication Details

Journal
International Journal of Radiation Biology
Published
2026-03-09
DOI
https://doi.org/10.1080/09553002.2026.2636304
Primary Topic
Effects of Radiation Exposure
Type
article
Field-Weighted Citation Impact
0.00
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article

Chromosomal damage in breast cancer patients undergoing different radiotherapy schemes

Magdalena Płódowska, Liv Veldeman, Ans Baeyens, Renu Dayal et al.
International Journal of Radiation Biology
Effects of Radiation Exposure
article

Chromosomal damage in breast cancer patients undergoing different radiotherapy schemes

Magdalena Płódowska, Liv Veldeman, Ans Baeyens, Renu Dayal, Aneta Węgierek-Ciuk, Halina Lisowska, J. Braziewicz, Prabodha Kumar Meher, Mirthe Vandenputte, Thea De Pauw, Andrzej Wojcik, Carlos Murillo, Lama Ramadan, Anne Vral
article en

Abstract

Shorter RT scheme with higher dose per fraction may mitigate cytogenetic damage in circulating lymphocytes, offering potential advantages in long-term safety profiles. In vitro chromosomal radiosensitivity, as assessed by CBMN assay is not a hallmark for second primary BC risk.

International Journal of Radiation Biology
College of the Holy Cross (US), Jan Kochanowski University (PL), Ghent University Hospital (BE), Ghent University (BE), Department of Health (TW), Cancer Research Institute Ghent (BE), Holy Cross University (PL), Wenner-Gren Foundations (SE)
Good health and well-being
Openalex Percentile: Top 30%
Effects of Radiation Exposure
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