Modulating efferocytosis in the intestinal epithelial cells during colorectal cancer

This suggests that these two approaches to clearing apoptotic cells is not sufficient to alter CRC progression. Targeting other phagocytic cell types or using other models of CRC might reveal a role (or otherwise) for efferocytosis in mitigating CRC in the future.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-03-09
DOI
https://doi.org/10.3389/fonc.2026.1740918
Primary Topic
Phagocytosis and Immune Regulation
Type
article
Field-Weighted Citation Impact
0.00
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article

Modulating efferocytosis in the intestinal epithelial cells during colorectal cancer

Tino Hochepied, Tania Løve Aaes, Lars Vereecke, Sze Men Choi et al.
Frontiers in Oncology
Phagocytosis and Immune Regulation
article

Modulating efferocytosis in the intestinal epithelial cells during colorectal cancer

Tino Hochepied, Tania Løve Aaes, Lars Vereecke, Sze Men Choi, Kodi S. Ravichandran, Laura Boeckaerts, Yunus Incik, Amanda Gonçalves, Evi Scheirlinckx
article en

Abstract

This suggests that these two approaches to clearing apoptotic cells is not sufficient to alter CRC progression. Targeting other phagocytic cell types or using other models of CRC might reveal a role (or otherwise) for efferocytosis in mitigating CRC in the future.

Frontiers in OncologyVol. 16
Vlaams Instituut voor Biotechnologie (BE), Ghent University (BE), Cancer Research Institute Ghent (BE)
Good health and well-being
Openalex Percentile: Top 28%
Phagocytosis and Immune Regulation
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