Kawasaki Disease Recurrence as a Diagnostic and Therapeutic Challenge: A Case Report

Kawasaki disease (KD) is a systemic vasculitis typically affecting children. It is usually self-limited, lasting less than two weeks without treatment; however, cardiovascular complications can occur, causing significant morbidity and mortality. Diagnosis is generally clinical, and treatment follows standardized guidelines, primarily intravenous immunoglobulin (IVIG) combined with acetylsalicylic acid (ASA), with or without corticosteroids, depending on the severity. Among KD types, refractory disease is defined by persistent fever after initial therapy, and recurrent disease is defined by the presence of at least three of the five classic KD criteria occurring at least 14 days after returning to baseline health. This case reports an 11-month-old female patient with recurrent KD without coronary complications after appropriate initial IVIG treatment.