Acute ST-Elevation Myocardial Infarction Complicating Infective Endocarditis: A Case Report and Review of Reported Outcomes After Revascularization

Acute myocardial infarction in the context of infective endocarditis is a dreadful complication. Various mechanisms have been proposed to explain this complication; embolization of fragments of valvular vegetations into the coronary tree is one possible mechanism. Early mortality with this complication is reportedly high. Moreover, outcomes after treatment, either with percutaneous or surgical intervention, are not well-described in the literature. We report a case of acute ST-elevation myocardial infarction complicating bacterial native aortic valve endocarditis. Despite aspiration of infective debris and stent implantation in the left anterior descending coronary artery, the patient died from cardiogenic and septic shock. We also summarize the literature reporting outcomes of such patients undergoing percutaneous coronary intervention and comparing them to the outcomes of patients undergoing surgical revascularization.

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Publication Details

Journal
Cureus
Published
2026-03-09
DOI
https://doi.org/10.7759/cureus.104883
Primary Topic
Infective Endocarditis Diagnosis and Management
Type
article
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article

Acute ST-Elevation Myocardial Infarction Complicating Infective Endocarditis: A Case Report and Review of Reported Outcomes After Revascularization

Hatim Al Lawati, Ahmed Shams, Mohamed M Madan
Cureus
Infective Endocarditis Diagnosis and Management
article

Acute ST-Elevation Myocardial Infarction Complicating Infective Endocarditis: A Case Report and Review of Reported Outcomes After Revascularization

Hatim Al Lawati, Ahmed Shams, Mohamed M Madan
article en

Abstract

Acute myocardial infarction in the context of infective endocarditis is a dreadful complication. Various mechanisms have been proposed to explain this complication; embolization of fragments of valvular vegetations into the coronary tree is one possible mechanism. Early mortality with this complication is reportedly high. Moreover, outcomes after treatment, either with percutaneous or surgical intervention, are not well-described in the literature. We report a case of acute ST-elevation myocardial infarction complicating bacterial native aortic valve endocarditis. Despite aspiration of infective debris and stent implantation in the left anterior descending coronary artery, the patient died from cardiogenic and septic shock. We also summarize the literature reporting outcomes of such patients undergoing percutaneous coronary intervention and comparing them to the outcomes of patients undergoing surgical revascularization.

Cureus
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Openalex Percentile: Top 30%
Infective Endocarditis Diagnosis and Management
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Acute ST-Elevation Myocardial Infarction Complicating Infective Endocarditis: A Case Report and Review of Reported Outcomes After Revascularization — Hatim Al Lawati, Ahmed Shams, et al. · Cureus (2026) | TGRS Research Map | TGRS