Case Report: A classical PSGN case with unusually prominent serosal manifestations and complement patterns that mimicked systemic autoimmune disease—highlighting diagnostic pitfalls and biopsy decision-making

This case underscores an unusual presentation of PSGN with serosal involvement-a manifestation reported only sporadically in literature. Recognition of such rare systemic features is crucial to avoid diagnostic delays or unnecessary immunosuppression. Supportive care alone led to favorable outcomes, reinforcing the self-limited nature of PSGN even in atypical presentations. It serves as a valuable reminder that atypical PSGN can present with multi-system inflammation, and a precise diagnostic approach integrating serology and clinical course is essential to avoid unnecessary intervention.

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Publication Details

Journal
Frontiers in Pediatrics
Published
2026-03-09
DOI
https://doi.org/10.3389/fped.2026.1759332
Primary Topic
Vasculitis and related conditions
Type
article
Field-Weighted Citation Impact
0.00
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article

Case Report: A classical PSGN case with unusually prominent serosal manifestations and complement patterns that mimicked systemic autoimmune disease—highlighting diagnostic pitfalls and biopsy decision-making

Sona Santy, Vinson James, Teresa Saverimuttu, Vindhya Kamath et al.
Frontiers in Pediatrics
Vasculitis and related conditions
article

Case Report: A classical PSGN case with unusually prominent serosal manifestations and complement patterns that mimicked systemic autoimmune disease—highlighting diagnostic pitfalls and biopsy decision-making

Sona Santy, Vinson James, Teresa Saverimuttu, Vindhya Kamath, Julie Steinberg
article en

Abstract

This case underscores an unusual presentation of PSGN with serosal involvement-a manifestation reported only sporadically in literature. Recognition of such rare systemic features is crucial to avoid diagnostic delays or unnecessary immunosuppression. Supportive care alone led to favorable outcomes, reinforcing the self-limited nature of PSGN even in atypical presentations. It serves as a valuable reminder that atypical PSGN can present with multi-system inflammation, and a precise diagnostic approach integrating serology and clinical course is essential to avoid unnecessary intervention.

Frontiers in PediatricsVol. 14
Good Samaritan Hospital (US), New York Institute of Technology (US), Good Samaritan Hospital (US)
Peace, Justice and strong institutions
Openalex Percentile: Top 28%
Vasculitis and related conditions
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