Wearable powered overground exoskeleton reduces dose-dependently the spasticity in individuals with spinal cord injury

Overground exoskeleton-assisted gait training effectively reduces spasticity and improves functional independence in individuals with SCI, with greater benefits observed at higher session frequencies. These findings support the integration of wearable powered exoskeletons into standard rehabilitation protocols for SCI.

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Publication Details

Journal
Spinal Cord
Published
2026-03-09
DOI
https://doi.org/10.1038/s41393-026-01181-6
Primary Topic
Botulinum Toxin and Related Neurological Disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Wearable powered overground exoskeleton reduces dose-dependently the spasticity in individuals with spinal cord injury

Giorgio Felzani, Carlotta Maria Manzia, Marco Franceschini, Sanaz Pournajaf et al.
Spinal Cord
Botulinum Toxin and Related Neurological Disorders
article

Wearable powered overground exoskeleton reduces dose-dependently the spasticity in individuals with spinal cord injury

Giorgio Felzani, Carlotta Maria Manzia, Marco Franceschini, Sanaz Pournajaf, Leonardo Pellicciari, Elena Sofia Cocco, Laura Simoncini, Rocco Salvatore Calabrò, Giovanni Morone
article en

Abstract

Overground exoskeleton-assisted gait training effectively reduces spasticity and improves functional independence in individuals with SCI, with greater benefits observed at higher session frequencies. These findings support the integration of wearable powered exoskeletons into standard rehabilitation protocols for SCI.

Spinal Cord
Vita-Salute San Raffaele University (IT), University of Campania "Luigi Vanvitelli" (IT), University of L'Aquila (IT), Istituto delle Scienze Neurologiche di Bologna (IT), IRCCS Ospedale San Raffaele (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT), Centro Neurolesi Bonino Pulejo (IT)
Dublin City University, Ministero della Salute, Università degli Studi dell'Aquila
Openalex Percentile: Top 36%
Botulinum Toxin and Related Neurological Disorders
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Wearable powered overground exoskeleton reduces dose-dependently the spasticity in individuals with spinal cord injury — Giorgio Felzani, Carlotta Maria Manzia, et al. · Spinal Cord (2026) | TGRS Research Map | TGRS