Regulation of Cellular Signaling by CUL5 is Dependent on Its Neddylation Status
These findings suggest that modification of CUL5 by NEDD8 may occur at multiple lysine residues and that multi-site neddylation may contribute to the diverse regulatory effects of CUL5 on cellular signaling and proliferation.
Authors
- Sarah Wieskamp
- Maria A. Burnatowska-Hledin (ORCID: https://orcid.org/0000-0003-2962-7424)
- Lauren Lee (ORCID: https://orcid.org/0009-0007-6330-0448)
- Lauren Kennington
- David Hayes (ORCID: https://orcid.org/0000-0002-1133-3471)
- Caroline Askonas (ORCID: https://orcid.org/0000-0003-3755-2805)
- Haley Lynch
- Sieun Ruth Lee (ORCID: https://orcid.org/0000-0002-6835-0248)
- Alyssa E. Johnson (ORCID: https://orcid.org/0000-0002-9356-2808)
- Henry Peabody
- Michael P. Hledin
- Abbey Schnell
- Skylar Sundquist
- Charlotte Turner
Institutions
- Hope College (US)
Publication Details
- Journal
- Cellular Physiology and Biochemistry
- Published
- 2026-03-09
- DOI
- https://doi.org/10.33594/000000855
- Primary Topic
- Ubiquitin and proteasome pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00