Analysis of factors associated with cervical cancer and precancerous lesions

To investigate factors influencing cervical cancer and precancerous lesions by collecting and analyzing clinical data and pathological results from 2,998 patients undergoing cervical biopsy; Pathological results and clinical data of 2,998 patients who underwent cervical biopsy at the gynecology outpatient clinic of a tertiary hospital in Hangzhou (January 2022-January 2023) were collected. Univariate analysis and multivariate unconditional logistic regression models were used to analyze relevant influencing factors; The results of univariate and multivariate analyses showed that cervical lesions were related to Human Papillomavirus (HPV) infection and the number of deliveries (P < 0.05) but were not related to age, number of pregnancies, number of abortions, use of condoms for contraception, and smoking (P > 0.05); Cervical cancer and precancerous lesions are associated with HPV infection and number of deliveries. It is imperative to implement a series of prevention and treatment measures to inhibit the onset and progression of cervical diseases, thereby reducing their incidence and mortality rates.

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Publication Details

Journal
Scientific Reports
Published
2026-03-09
DOI
https://doi.org/10.1038/s41598-025-32215-3
Primary Topic
Cervical Cancer and HPV Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Analysis of factors associated with cervical cancer and precancerous lesions

Dan Hu, Xiangqian Xu, Yan Zhao, Weiwei Qian et al.
Scientific Reports
Cervical Cancer and HPV Research
article

Analysis of factors associated with cervical cancer and precancerous lesions

Dan Hu, Xiangqian Xu, Yan Zhao, Weiwei Qian, Shaoqin Sheng, Mengnan Han
article en

Abstract

To investigate factors influencing cervical cancer and precancerous lesions by collecting and analyzing clinical data and pathological results from 2,998 patients undergoing cervical biopsy; Pathological results and clinical data of 2,998 patients who underwent cervical biopsy at the gynecology outpatient clinic of a tertiary hospital in Hangzhou (January 2022-January 2023) were collected. Univariate analysis and multivariate unconditional logistic regression models were used to analyze relevant influencing factors; The results of univariate and multivariate analyses showed that cervical lesions were related to Human Papillomavirus (HPV) infection and the number of deliveries (P < 0.05) but were not related to age, number of pregnancies, number of abortions, use of condoms for contraception, and smoking (P > 0.05); Cervical cancer and precancerous lesions are associated with HPV infection and number of deliveries. It is imperative to implement a series of prevention and treatment measures to inhibit the onset and progression of cervical diseases, thereby reducing their incidence and mortality rates.

Scientific ReportsVol. 16(1)
Zhejiang Chinese Medical University (CN), Hangzhou Normal University (CN), Ningbo No. 2 Hospital (CN), Hangzhou Women’s Hospital (CN), Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN), Ningbo No.6 Hospital (CN)
Science and Technology Program of Zhejiang Province
Good health and well-being
Openalex Percentile: Top 30%
Cervical Cancer and HPV Research
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Analysis of factors associated with cervical cancer and precancerous lesions — Dan Hu, Xiangqian Xu, et al. · Scientific Reports (2026) | TGRS Research Map | TGRS