Neoadjuvant camrelizumab combined with radiotherapy as a chemotherapy-sparing approach for resectable locally advanced esophageal squamous cell carcinoma: a phase II clinical trial (ESOCORT-NIRT)

Neoadjuvant camrelizumab plus radiotherapy showed low toxicity, pathologic tumor regression, and favorable postoperative outcomes in resectable esophageal squamous cell carcinoma. This chemotherapy-sparing approach may be an alternative for patients who are unsuitable for or intolerant of standard chemotherapy-based neoadjuvant regimens.

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Publication Details

Journal
BMC Medicine
Published
2026-03-09
DOI
https://doi.org/10.1186/s12916-026-04781-4
Primary Topic
Esophageal Cancer Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Neoadjuvant camrelizumab combined with radiotherapy as a chemotherapy-sparing approach for resectable locally advanced esophageal squamous cell carcinoma: a phase II clinical trial (ESOCORT-NIRT)

Yizhou Huang, Maohui Chen, Zhenyuan Yang, Hongmu Li et al.
BMC Medicine
Esophageal Cancer Research and Treatment
article

Neoadjuvant camrelizumab combined with radiotherapy as a chemotherapy-sparing approach for resectable locally advanced esophageal squamous cell carcinoma: a phase II clinical trial (ESOCORT-NIRT)

Yizhou Huang, Maohui Chen, Zhenyuan Yang, Hongmu Li, T. Zeng, Chuanquan Lin, Bin Zheng, Chun Chen, Wei Li, Cheng Chen, Benhua Xu, Shuliang Zhang
article en

Abstract

Neoadjuvant camrelizumab plus radiotherapy showed low toxicity, pathologic tumor regression, and favorable postoperative outcomes in resectable esophageal squamous cell carcinoma. This chemotherapy-sparing approach may be an alternative for patients who are unsuitable for or intolerant of standard chemotherapy-based neoadjuvant regimens.

BMC Medicine
Fujian Medical University (CN), Education Department of Fujian Province (CN), Union Hospital (CN), Fuzhou University (CN)
Good health and well-being
Openalex Percentile: Top 29%
Esophageal Cancer Research and Treatment
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