The In Vitro Antibacterial Effects of Genipin Against Pathogens Commonly Associated With Infected Ulcerative Keratitis: A Canine Preliminary Study
Genipin exhibited promising antibacterial activity against all tested isolates, including MRSP. We suggest that genipin acts as a concentration-dependent antimicrobial agent, demonstrating bactericidal activity at higher concentrations against staphylococci. P. aeruginosa appeared less susceptible to the short-term effects of genipin. Further investigation is warranted to elucidate genipin's full antimicrobial potential and clinical performance.
Authors
- Robert P. L. Wisse (ORCID: https://orcid.org/0000-0002-2844-9868)
- Arnoud Smit
- Els M. Broens (ORCID: https://orcid.org/0000-0003-1312-6115)
- Inge J. M. Slenter (ORCID: https://orcid.org/0000-0002-4061-6542)
- Marian J. Broekhuizen-Stins
- Linda van der Graaf-van Bloois
- Bas W. Schipper
- Sylvia C. Djajadiningrat-Laanen
Institutions
- University of Applied Sciences Utrecht (NL)
- Utrecht University (NL)
- University Medical Center Utrecht (NL)
- Pension Fund for Care and Well-Being (NL)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2026-03-09
- DOI
- https://doi.org/10.1167/iovs.67.3.18
- Primary Topic
- Saffron Plant Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00