Effects of Various Anti-Diabetic Drugs on the Risk of Fractures in Older Women with Type 2 Diabetes Mellitus

In older women with T2DM, TZD use was associated with increased VF and NVF risks, particularly among those with normal or osteopenic BMD and normal BMI. SGLT2i showed no increased risk, but further large-scale studies are needed to confirm its skeletal safety.

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Publication Details

Journal
Journal of Bone Metabolism
Published
2026-02-28
DOI
https://doi.org/10.11005/jbm.25.895
Primary Topic
Bone health and osteoporosis research
Type
article
Field-Weighted Citation Impact
0.00

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article

Effects of Various Anti-Diabetic Drugs on the Risk of Fractures in Older Women with Type 2 Diabetes Mellitus

Kyoung Jin Kim, Su Jin Kwon, Ha Young Kim, So Young Park et al.
Journal of Bone Metabolism
Bone health and osteoporosis research
article

Effects of Various Anti-Diabetic Drugs on the Risk of Fractures in Older Women with Type 2 Diabetes Mellitus

Kyoung Jin Kim, Su Jin Kwon, Ha Young Kim, So Young Park, Seong Hee Ahn, Kyoung Min Kim
article en

Abstract

In older women with T2DM, TZD use was associated with increased VF and NVF risks, particularly among those with normal or osteopenic BMD and normal BMI. SGLT2i showed no increased risk, but further large-scale studies are needed to confirm its skeletal safety.

Journal of Bone MetabolismVol. 33(1)
Ulsan College (KR), Yonsei University (KR), Korea University (KR), Severance Hospital (KR), Kyung Hee University (KR), University of Ulsan (KR), Gangneung Asan Hospital (KR), Inha University Hospital (KR)
National Health Insurance Service
Good health and well-being
Openalex Percentile: Top 29%
Bone health and osteoporosis research
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