3D printed implant structure for breast reconstruction and systematic drug delivery for preventing the reoccurrence of cancer

Breast cancer is one of the most common and deadly cancers among women worldwide. The treatment of breast cancer often involves mastectomy, which can cause physical and psychological distress to the patients, affecting their quality of life and self-esteem [1]. Therefore, the surgical intervention of breast cancer should not include only the removal of a tumor, but also psychological support by restoring the natural shape of the breast and achieving proper aesthetic for each patient. Conventional breast reconstruction techniques have several limitations, such as donor site morbidity, implant failure, infection, and poor cosmetic outcome. Moreover, breast cancer patients often require systemic chemotherapy or hormone therapy after surgery, which can cause severe side effects and complications. In this article, it is proposed a novel implant based 3d printed structure for breast reconstruction and systematic drug delivery. The implant consists of a biodegradable scaffold that is 3d printed with a customized shape, coated with Polydopamine and Alginate, and sized to fit the patient’s chest. The implant provides mechanical support, aesthetic improvement and can also enhance the efficacy and safety of chemotherapy or hormone therapy by delivering treatment directly to the target site through a channel system. The aim of the article presented here is a proposed process protocol for obtaining this prosthesis.