<scp>16S rRNA</scp> Amplicon Sequencing of the Intraoperative Surgical Site Demonstrates an Aberrant Microbiota Which Can Predict Colorectal Surgical Site Infection

To the best of our knowledge this is the first study to demonstrate an aberrant intraoperative microbiota of the surgical site associated with subsequent infection. Pending validation studies, this provides a target for the strategic manipulation of the surgical site to reduce the burden of infection.

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Publication Details

Journal
ANZ Journal of Surgery
Published
2026-03-09
DOI
https://doi.org/10.1111/ans.70578
Primary Topic
Surgical site infection prevention
Type
article
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article

16S rRNA Amplicon Sequencing of the Intraoperative Surgical Site Demonstrates an Aberrant Microbiota Which Can Predict Colorectal Surgical Site Infection

Shaveen Kanakaratne, R. Carroll, Natalie Lott, Michelle Zhao et al.
ANZ Journal of Surgery
Surgical site infection prevention
article

16S rRNA Amplicon Sequencing of the Intraoperative Surgical Site Demonstrates an Aberrant Microbiota Which Can Predict Colorectal Surgical Site Infection

Shaveen Kanakaratne, R. Carroll, Natalie Lott, Michelle Zhao, Veral Vishnoi, Spencer Smith, Emily C. Hoedt, Peter Pockney, Simon Keely
article en

Abstract

To the best of our knowledge this is the first study to demonstrate an aberrant intraoperative microbiota of the surgical site associated with subsequent infection. Pending validation studies, this provides a target for the strategic manipulation of the surgical site to reduce the burden of infection.

ANZ Journal of Surgery
John Hunter Hospital (AU), Hunter Medical Research Institute (AU), Calvary Mater Newcastle Hospital (AU), University of Newcastle Australia (AU)
Good health and well-being
Openalex Percentile: Top 29%
Surgical site infection prevention
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<scp>16S rRNA</scp> Amplicon Sequencing of the Intraoperative Surgical Site Demonstrates an Aberrant Microbiota Which Can Predict Colorectal Surgical Site Infection — Shaveen Kanakaratne, R. Carroll, et al. · ANZ Journal of Surgery (2026) | TGRS Research Map | TGRS