Comprehensive evaluation of triglyceride glucose index–a body shape index (TyG–ABSI) for incident peripheral artery disease: data-driven phenotyping and machine learning-based risk prediction in the UK Biobank

TyG-ABSI is a robust, independent predictor of long-term PAD risk. Data-driven phenotyping and interpretable machine learning facilitate more precise risk stratification. Logistic regression offers optimal performance and interpretability, holding potential clinical utility for individualized PAD risk prediction.

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Publication Details

Journal
Cardiovascular Diabetology
Published
2026-03-09
DOI
https://doi.org/10.1186/s12933-026-03116-0
Primary Topic
Peripheral Artery Disease Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Comprehensive evaluation of triglyceride glucose index–a body shape index (TyG–ABSI) for incident peripheral artery disease: data-driven phenotyping and machine learning-based risk prediction in the UK Biobank

Wei Zhao, Xiaolu Li, Zuoguan G. Chen, Xihao Zhang et al.
Cardiovascular Diabetology
Peripheral Artery Disease Management
article

Comprehensive evaluation of triglyceride glucose index–a body shape index (TyG–ABSI) for incident peripheral artery disease: data-driven phenotyping and machine learning-based risk prediction in the UK Biobank

Wei Zhao, Xiaolu Li, Zuoguan G. Chen, Xihao Zhang, Chengran Lu, Bo Zhang, Yong Lan, Yongpeng Diao, Zhiyuan Wu, Yaming Guo, Yongjun Li, Yifan Cao
article en

Abstract

TyG-ABSI is a robust, independent predictor of long-term PAD risk. Data-driven phenotyping and interpretable machine learning facilitate more precise risk stratification. Logistic regression offers optimal performance and interpretability, holding potential clinical utility for individualized PAD risk prediction.

Cardiovascular Diabetology
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking University (CN), Peking Union Medical College Hospital (CN), Peking University People's Hospital (CN), University of Chinese Academy of Sciences (CN)
Openalex Percentile: Top 29%
Peripheral Artery Disease Management
DOIOpen Access PDFOpenAlex
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Comprehensive evaluation of triglyceride glucose index–a body shape index (TyG–ABSI) for incident peripheral artery disease: data-driven phenotyping and machine learning-based risk prediction in the UK Biobank — Wei Zhao, Xiaolu Li, et al. · Cardiovascular Diabetology (2026) | TGRS Research Map | TGRS