Tissue characteristics in a traumatised immature necrotic incisor after unsuccessful regenerative endodontic treatment: an immunohistological case report

The newly formed intracanal tissues demonstrated limited similarity to intact odontogenic tissues. Both inflammatory root resorption and ankylosis-related replacement resorption, likely associated with the initial luxation injury, were observed. The presence of cholesterol crystal deposits represents a novel finding that may provide new insights into the biological processes occurring after RET. As cellular events following RET cannot be fully controlled clinically, the risk of unfavourable outcomes should be considered carefully, particularly in cases involving luxation injuries.