Comprehensive Shotgun Metagenomic Profiling of Antibiotic Resistance Genes in Sheep and Goat Farming Environments
These findings highlight small ruminant farm environments as potential reservoirs of clinically relevant ARGs, including WHO highest priority critically important antimicrobial (HPCIA) resistance genes for macrolides (<i>mph(c)</i>, <i>erm(f)</i>, <i>erm(b)</i>) and fluoroquinolones (<i>qnrD1</i>), as well as critically important antimicrobial (CIA) resistance genes for glycopeptides (<i>vanR-SC</i>, <i>vanR-O</i>) and aminoglycosides (<i>str</i>, <i>aadA</i>), supporting the need to incorporate these environments into surveillance strategies.
Authors
- Pedro Carreira (ORCID: https://orcid.org/0000-0003-3376-7040)
- João R. Mesquita (ORCID: https://orcid.org/0000-0001-8769-8103)
- Fernando Esteves (ORCID: https://orcid.org/0000-0003-0589-0746)
- Sara Gomes-Gonçalves (ORCID: https://orcid.org/0000-0001-8374-3739)
- Guilherme Moreira (ORCID: https://orcid.org/0009-0002-2828-7202)
- Jaqueline T. Bento (ORCID: https://orcid.org/0009-0003-1324-8902)
- Pedro Caseiro
- Maria Aires Pereira
- Alexandra Lameira Baptista
- Joana Mourão
- Rita Cruz
- Luís Figueira
Institutions
- Universidade Politécnica de Castelo Branco (PT)
- University of Trás-os-Montes and Alto Douro (PT)
- Universidade do Porto (PT)
- SGS (Portugal) (PT)
- Polytechnic Institute of Viseu (PT)
- Universidade Nova de Lisboa (PT)
- Technical University of Denmark (DK)
Publication Details
- Journal
- Antibiotics
- Published
- 2026-03-09
- DOI
- https://doi.org/10.3390/antibiotics15030277
- Primary Topic
- Pharmaceutical and Antibiotic Environmental Impacts
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fundação para a Ciência e a Tecnologia