Study of young psychiatric patients shows potential preventive benefit of doxycycline
A study using an emulated target trial design has found a reduced long‐term risk of a diagnosis of schizophrenia in adolescents who had received psychiatric treatment and had incidentally also received treatment with the broad‐spectrum tetracycline antibiotic doxycycline. Risk of schizophrenia at 10 years was significantly lower in individuals who had taken doxycycline compared with those receiving other antibiotics.
Publication Details
- Journal
- The Brown University Psychopharmacology Update
- Published
- 2026-02-23
- DOI
- https://doi.org/10.1002/pu.31418
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00