Analysis of PIK3CA mutations in the lysate of sentinel lymph nodes in patients with early breast cancer
Assessment of tumor-derived mutated DNA in SNs may be a useful technique to detect SN metastasis, as confirmed by ddPCR analysis. Further analyses, using data from a greater number of patients, are necessary to determine whether the results of whole-genome and whole-exome sequencing can be applied to other genes.
Authors
- Tomonori Tanei (ORCID: https://orcid.org/0000-0003-2183-8681)
- Chieko Mishima
- Yoshiaki Sota (ORCID: https://orcid.org/0000-0001-5963-652X)
- Nanae Masunaga (ORCID: https://orcid.org/0000-0002-6164-5107)
- Yasufumi Sato (ORCID: https://orcid.org/0000-0002-6761-7553)
- Sung Ae Park
- Masami Tsukabe (ORCID: https://orcid.org/0009-0009-3284-0833)
- Ryu Tokui
- Kenzo Shimazu (ORCID: https://orcid.org/0000-0002-0837-2357)
- Takanori Kin
- Tetsuhiro Yoshinami
Institutions
- Osaka International Cancer Institute (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-03-09
- DOI
- https://doi.org/10.3389/fonc.2026.1658786
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00