Dual dimensions of sensitization: age-stratified and disease-associated sIgE profiles in pediatric eczema and urticaria
This study identified distinct age-dependent sIgE sensitization profiles, while disease-associated differences were attenuated after accounting for age and sex. These findings highlight age as a primary dimension for sensitization risk stratification and underscore the clinical value of integrating sIgE monitoring with other biomarkers, such as eosinophils and hemoglobin.
Authors
- Kaijie Gao
- Panpan Fang (ORCID: https://orcid.org/0000-0002-4165-716X)
- Xiang Feng (ORCID: https://orcid.org/0000-0001-5772-2854)
- Na Chen (ORCID: https://orcid.org/0009-0003-7214-2964)
- Junmei Yang
- Ci Li (ORCID: https://orcid.org/0009-0005-4459-1759)
- Liu Yang (ORCID: https://orcid.org/0000-0001-9192-0520)
- Zhiwei Zhu
- Jiajia Ni
Institutions
- Unitika (Japan) (JP)
- Zhengzhou Children's Hospital (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2026-03-09
- DOI
- https://doi.org/10.3389/fnut.2026.1763720
- Primary Topic
- Urticaria and Related Conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00