Prescription patterns of hypnotics for children and adolescents in Japan: A descriptive epidemiologic study using a claims database
Melatonin was most frequently prescribed in children for a longer duration than other hypnotics, while MRAs were prescribed across all age groups and DORAs mainly to adolescents. These age-specific patterns suggest that the drug selection was conducted according to patient's age, since pediatric insomnia might be correlated with psychiatric disorders related to developmental stage. Future research should investigate the long-term effects of hypnotic prescriptions with consideration of comorbid conditions.
Authors
- Kayoko Mizuno (ORCID: https://orcid.org/0000-0002-6084-9845)
- Kazuo Mishima (ORCID: https://orcid.org/0000-0003-1182-1181)
- Michinori Koebis
- Koji Kawakami (ORCID: https://orcid.org/0000-0002-7477-4071)
- Yukinori Sakata
- Mika Ishii
- Naoki Kubota (ORCID: https://orcid.org/0000-0002-1292-0897)
- Hiroshi Ohashi (ORCID: https://orcid.org/0000-0002-3759-3757)
- Toshiki Fukasawa
- Sachiko Tanaka-Mizuno
- Margaret Moline
- Kenichi Fujimoto
- Motomu Suga
Institutions
- Teikyo Heisei University (JP)
- Kobe Pharmaceutical University (JP)
- Akita University (JP)
- Kyoto University (JP)
- National Mie Hospital (JP)
- Eisai (United States) (US)
- Eisai (Japan) (JP)
Publication Details
- Journal
- SLEEP
- Published
- 2026-03-07
- DOI
- https://doi.org/10.1093/sleep/zsag067
- Primary Topic
- Sleep and related disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00