Boost Approaches in Patients Undergoing Postoperative Radiotherapy

The use of breast conservation surgery for early-stage breast cancer is common, and adjuvant radiotherapy is often recommended to reduce the risk of ipsilateral breast tumor recurrence. Historical trials have used sequential boost techniques with favorable outcomes with reduction in local recurrence and acceptable cosmetic outcomes. In recent years, there has been renewed interest in incorporating a concurrent tumor bed boost to reduce the number of radiation treatments delivered. This focused review summarizes the literature surrounding the indications, outcomes, and treatment planning considerations for radiation tumor bed boost for early-stage breast cancer patients.

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Publication Details

Journal
Journal of Surgical Oncology
Published
2026-03-08
DOI
https://doi.org/10.1002/jso.70228
Primary Topic
Breast Cancer Treatment Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Boost Approaches in Patients Undergoing Postoperative Radiotherapy

Gary M. Freedman, Neil K. Taunk, Abigail Pepin, Megan Kassick et al.
Journal of Surgical Oncology
Breast Cancer Treatment Studies
article

Boost Approaches in Patients Undergoing Postoperative Radiotherapy

Gary M. Freedman, Neil K. Taunk, Abigail Pepin, Megan Kassick, Neil D. Almeida, Simon Fung‐Kee‐Fung
article en

Abstract

The use of breast conservation surgery for early-stage breast cancer is common, and adjuvant radiotherapy is often recommended to reduce the risk of ipsilateral breast tumor recurrence. Historical trials have used sequential boost techniques with favorable outcomes with reduction in local recurrence and acceptable cosmetic outcomes. In recent years, there has been renewed interest in incorporating a concurrent tumor bed boost to reduce the number of radiation treatments delivered. This focused review summarizes the literature surrounding the indications, outcomes, and treatment planning considerations for radiation tumor bed boost for early-stage breast cancer patients.

Journal of Surgical Oncology
Roswell Park Comprehensive Cancer Center (US), University of Pennsylvania (US)
Life in Land
Openalex Percentile: Top 29%
Breast Cancer Treatment Studies
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