Review: Research does not support most promoted medical uses of cannabis

Evidence from randomized clinical trials generally does not support use of cannabis or cannabinoids for most medical conditions, a review based on 124 studies has concluded. Authors of the review advise clinicians to discuss safety‐related measures with patients who use cannabis or cannabinoids for medical reasons, including warning them against concurrent use of cannabis with alcohol or benzodiazepines. Results of the review were published online Nov. 26, 2025 in JAMA .

Publication Details

Journal
The Brown University Psychopharmacology Update
Published
2026-02-23
DOI
https://doi.org/10.1002/pu.31415
Primary Topic
Cannabis and Cannabinoid Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Review: Research does not support most promoted medical uses of cannabis

The Brown University Psychopharmacology Update
Cannabis and Cannabinoid Research
article

Review: Research does not support most promoted medical uses of cannabis

article en

Abstract

Evidence from randomized clinical trials generally does not support use of cannabis or cannabinoids for most medical conditions, a review based on 124 studies has concluded. Authors of the review advise clinicians to discuss safety‐related measures with patients who use cannabis or cannabinoids for medical reasons, including warning them against concurrent use of cannabis with alcohol or benzodiazepines. Results of the review were published online Nov. 26, 2025 in JAMA .

The Brown University Psychopharmacology UpdateVol. 37(3)
Good health and well-being
Openalex Percentile: Top 29%
Cannabis and Cannabinoid Research
DOISourceOpenAlex
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Review: Research does not support most promoted medical uses of cannabis · The Brown University Psychopharmacology Update (2026) | TGRS Research Map | TGRS