Establishment of Reference Interval for <scp>CA72</scp> ‐4 in Healthy Adults in Shenzhen, China

An upper reference limit of 8.5 U/mL for CA72-4 in Shenzhen healthy adults-higher than the manufacturer's value-reduces false positives in health screening. Slight age-related increases suggest cautious interpretation in the elderly. This study provides an important reference for region-specific tumor marker intervals in Shenzhen and similar populations.

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Publication Details

Journal
Journal of Clinical Laboratory Analysis
Published
2026-03-08
DOI
https://doi.org/10.1002/jcla.70188
Primary Topic
Colorectal Cancer Screening and Detection
Type
article
Field-Weighted Citation Impact
0.00
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article

Establishment of Reference Interval for CA72 ‐4 in Healthy Adults in Shenzhen, China

Mengting An, Dong Zhang, Junjie Wan, Zhiling Xu
Journal of Clinical Laboratory Analysis
Colorectal Cancer Screening and Detection
article

Establishment of Reference Interval for CA72 ‐4 in Healthy Adults in Shenzhen, China

Mengting An, Dong Zhang, Junjie Wan, Zhiling Xu
article en

Abstract

An upper reference limit of 8.5 U/mL for CA72-4 in Shenzhen healthy adults-higher than the manufacturer's value-reduces false positives in health screening. Slight age-related increases suggest cautious interpretation in the elderly. This study provides an important reference for region-specific tumor marker intervals in Shenzhen and similar populations.

Journal of Clinical Laboratory Analysis
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking Union Medical College Hospital (CN)
Good health and well-being
Openalex Percentile: Top 29%
Colorectal Cancer Screening and Detection
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