Changes in Cellular Senescence Biomarkers Across Individuals at Different Stages of HIV Infection Before and After a Year on Antiretroviral Therapy
HIV infection promotes persistent cellular senescence despite ART in advanced and chronic infection. Thus, future senolytic or senomorphic strategies against cellular senescence may reduce chronic inflammation and aging-related complications in PWH.
Authors
- Víctor Casanova (ORCID: https://orcid.org/0000-0002-4917-260X)
- Núria Climent (ORCID: https://orcid.org/0000-0002-0791-656X)
- Cristina Rovira
- Josep Mallolas (ORCID: https://orcid.org/0000-0002-8365-141X)
- Andrea Rodríguez-Agustín
- Rubén Ayala-Suárez (ORCID: https://orcid.org/0000-0002-1271-6466)
- J Alcamí
- José M Miró
- Iván Chivite
- Sonsoles Sánchez-Palomino
- Esteban Martínez
- María José Maleno
- Juan Ambrosioni
- Elisa De Lazzari
Institutions
- Instituto de Salud Carlos III (ES)
- Hospital Clínic de Barcelona (ES)
- Fundació Clínic per a la Recerca Biomèdica (ES)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- Instituto de Investigación de Enfermedades Raras (ES)
- Universitat de Barcelona (ES)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2026-02-28
- DOI
- https://doi.org/10.1093/infdis/jiag133
- Primary Topic
- Telomeres, Telomerase, and Senescence
- Type
- article
- Field-Weighted Citation Impact
- 0.00