Dosimetric impact of endoscopic titanium clips in photon and proton radiotherapy for esophageal cancer
Endoscopic titanium clips introduce only minor, clinically insignificant dose perturbations in photon and proton esophageal radiotherapy. Proton sensitivity to local heterogeneities is effectively mitigated by robust optimization. These findings support the dosimetric safety and reliability of titanium clips as localization markers in contemporary treatment planning.
Authors
- Chuanchuan Yu (ORCID: https://orcid.org/0000-0003-3450-9457)
- Xu Li (ORCID: https://orcid.org/0000-0003-0684-6923)
- Jun Han (ORCID: https://orcid.org/0000-0001-6393-7042)
- Xiaorong Dong
- Bingyue Wang
- R. Zhou
- Pengyuan Qi
- Xiaohui Wang
- Ningjing Siah
- Sheng Zhang
Institutions
- Sun Yat-sen University (CN)
- China Three Gorges University (CN)
- Second Hospital of Yichang (CN)
- Wuhan Union Hospital (CN)
- Yichang Central People's Hospital (CN)
- Union Hospital (US)
- Union Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-03-09
- DOI
- https://doi.org/10.3389/fonc.2026.1769701
- Primary Topic
- Advanced Radiotherapy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hubei Province