Adaptive immune and platelet activation during the maintenance phase of therapy in adults with B cell acute lymphoblastic leukemia

Adult patients with B-ALL undergoing maintenance therapy exhibits increased lymphocyte and platelet activation, which may be associated with an elevated thrombotic risk despite normal D-dimer levels.

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Publication Details

Journal
Platelets
Published
2026-03-09
DOI
https://doi.org/10.1080/09537104.2026.2636463
Primary Topic
Acute Lymphoblastic Leukemia research
Type
article
Field-Weighted Citation Impact
0.00
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article

Adaptive immune and platelet activation during the maintenance phase of therapy in adults with B cell acute lymphoblastic leukemia

Zekhethelo Alondwe Mkhwanazi, Tawanda M. Nyambuya, Bongani B. Nkambule, Edwig Shingenge
Platelets
Acute Lymphoblastic Leukemia research
article

Adaptive immune and platelet activation during the maintenance phase of therapy in adults with B cell acute lymphoblastic leukemia

Zekhethelo Alondwe Mkhwanazi, Tawanda M. Nyambuya, Bongani B. Nkambule, Edwig Shingenge
article en

Abstract

Adult patients with B-ALL undergoing maintenance therapy exhibits increased lymphocyte and platelet activation, which may be associated with an elevated thrombotic risk despite normal D-dimer levels.

PlateletsVol. 37(1)
Namibia University of Science and Technology (NA), University of the Witwatersrand (ZA), University of KwaZulu-Natal (ZA)
Good health and well-being
Openalex Percentile: Top 34%
Acute Lymphoblastic Leukemia research
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