Mesenchymal stromal cell therapy restores intestinal integrity and attentuates inflammation in a preterm piglet model of necrotizing enterocolitis
This is the first study to demonstrate therapeutic benefit of MSCs in a preterm piglet NEC model, supporting their potential use in translational NEC therapies.
Authors
- Troy A. Markel (ORCID: https://orcid.org/0000-0002-6429-2976)
- Timothy B. Lescun (ORCID: https://orcid.org/0000-0002-9475-4908)
- Chelsea Hunter (ORCID: https://orcid.org/0000-0002-7362-5277)
- Jianyun Liu (ORCID: https://orcid.org/0000-0002-6731-0375)
- Christa J. Crain
- Krishna Manohar (ORCID: https://orcid.org/0000-0002-3576-8584)
- Jasmine Lee (ORCID: https://orcid.org/0000-0002-3015-2975)
- Robyn McCain
- John Brokaw
- Fikir Mesfin
- W. Chris Shelley
- Sharon Joseph
Institutions
- Purdue University West Lafayette (US)
- Indiana University Hospital (US)
- Riley Hospital for Children (US)
- Indiana University – Purdue University Indianapolis (US)
Publication Details
- Journal
- Pediatric Surgery International
- Published
- 2026-03-09
- DOI
- https://doi.org/10.1007/s00383-026-06324-7
- Primary Topic
- Infant Nutrition and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- School of Medicine, Indiana University